Associate Bioinformatician Position

Day Zero Diagnostics is a bacterial genomics start-up in Boston that is seeking to recruit a highly motivated bioinformatician to join our team. At Day Zero Diagnostics we are modernizing the way infectious diseases are diagnosed and treated by developing a rapid diagnostic that sequences the genomes of pathogenic bacteria, and then uses machine learning methods to identify the cause of the clinical infection.

As a bioinformatician, you will work with a senior computational biologist to implement NGS data pipelines and microbial genomic data analysis tools. These tools will be used both to aid internal R&D projects, and to provide lab-based services for customer-facing projects. Candidates will gain experience in a multidisciplinary and fast-paced start-up environment, and will have ample opportunities to acquire new skills, work closely with an accomplished team, and communicate results through patents, conference presentations, and peer-reviewed publications while working in a supportive and energetic environment. We value intellectual curiosity and a strong work ethic, and look for candidates who are both excited to contribute their expertise and eager to broaden their skillset to new areas.


Under the direction of a senior computational biologist, the applicant independently carries out bioinformatics and software engineering tasks, including:

  • Implementing analytical tools and reports on hospital outbreaks of bacterial infections
  • Maintaining pipelines for NGS data, including Illumina and MinION sequencing data
  • Execute genomic-based lab services for clinical samples
  • Maintain organized, tested code and corresponding documentation
  • Present data within and outside of the company at meetings and symposia
  • Write, edit, and submit manuscripts/abstracts/grants detailing the results of the project
  • Work closely within the group and with outside collaborators
  • Maintain close communications with the team regarding progress


  • Bachelor's or Masters Degree in Computer Science, Bioinformatics, Computational Biology, or equiv.
  • Relevant experience in bioinformatics with a strong preference for microbial genomics experience
  • Fluency in Python, and Linux; familiarity with SQL and git helpful
  • Familiarity with NGS data and standard bioinformatics tools (alignment, variant calling, assembly)
  • Familiarity with ONT MinION data helpful
  • Highly motivated and independent, with the ability to work in a dynamic team environment
  • Strong oral and written communications skills
  • Excellent organizational skills and attention to detail
  • Flexibility to occasionally work evenings or weekends

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