Computational Biologist Position

Day Zero Diagnostics is a bacterial genomics startup in Boston that is seeking to recruit a highly motivated computational biologist to join our team. At Day Zero Diagnostics we are modernizing the way infectious diseases are diagnosed and treated by developing a rapid diagnostic that sequences the genomes of pathogenic bacteria, and then uses machine learning methods to provide the species ID and antibiotic resistance profile. We value intellectual curiosity and a strong work ethic. As a computational biologist, you will be responsible for managing NGS data pipelines and developing microbial genomic data analysis tools. These tools will be used both to aid internal R&D projects, and to provide lab-based services for customer-facing projects. Candidates will gain experience in a multidisciplinary and fast-paced startup environment, and will have ample opportunities to acquire new skills, work closely with an accomplished team, and communicate results through patents, conference presentations, and peer-reviewed publications while working in a supportive and energetic environment. We value intellectual curiosity and a strong work ethic, and look for candidates who are both excited to contribute their expertise and eager to broaden their skillset to new areas.


Under the supervision of the director of computational biology, the applicant independently carries out data analysis tasks, including: * Develop and maintain pipelines for NGS data, including Illumina and MinION sequencing data * Execute genomic-based lab services for clinical samples * Provide genomic expertise on microbial mechanisms of resistance and virulence * Provide bioinformatic support for the team * Maintain organized, tested code and corresponding documentation * Present data within and outside of the company at meetings and symposia * Write, edit, and submit manuscripts/abstracts/grants detailing the results of the project * Work closely within the group and with outside collaborators * Maintain close communications with the team regarding progress


  • PhD with relevant experience in bioinformatics with a strong preference for microbial genomics expertise
  • Fluency in Python, and Linux; familiarity with SQL and git helpful
  • Familiarity with NGS data; familiarity with bioinformatics tools (alignment, variant calling, assembly, annotation); familiarity with ONT MinION data helpful
  • Highly motivated and independent, with the ability to work in a dynamic team environment
  • Strong oral and written communications skills
  • Excellent organizational skills and attention to detail

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