Healthcare-associated infections (HAIs) affect 4-5% of hospitalized patients in the U.S. and result in 99,000 deaths per year. The rising prevalence of multi-drug resistant organisms has made HAIs particularly dangerous, and has increased the need for rapid, effective interventions to control an outbreak.

Day Zero Diagnostics introduces the precision and clarity of whole genome sequencing to outbreak investigations with epiXact (pronounced epi-zact), a rapid turnaround sequencing and analysis service for infection control teams. The epiXact service provides definitive determination of pathogen relatedness in a suspected outbreak using single-nucleotide polymorphism comparisons of the whole genome. Sequencing and analysis are performed by experts in the field and an easy-to-read report is provided within 1-2 days.

Outbreak investigations involve high stake decisions and the imprecise and subjective process used today to identify a transmission event leaves much to be desired. epiXact enables infection control teams to confidently avoid unnecessary interventions when a suspected transmission can be ruled out and to drive full organizational responses when an outbreak is real.

Case Studies

Our fast response team is here to support you in providing definitive and actionable results so you can quickly rule in or rule out an HAI transmission. Click on one of the case studies below to read about our work in action.

To Screen or Not to Screen: Using epiXact to Determine if Large Scale Healthcare Worker Screening for MRSA is Merited
Mobilizing a Full Response: Determination of Carbapenem-Resistant Acinetobacter Baumannii Outbreak in the Surgical ICU Using epiXact

Mobilizing epiXact for Outbreak Investigations

Click here to download more information on the epiXact service or to understand how to get started on your first investigation. To contact us immediately, submit a service request below or email us at Our team will contact you promptly.

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