Using genome sequencing & machine learning to modernize infectious disease diagnosis and treatment


Antibiotic resistance is creating a public health crisis. Patients with a severe infection can die within hours, but current diagnostics for antibiotic resistance take 2 days or longer. At DZD, we are developing a rapid, whole genome sequencing-based diagnostic that identifies the strain and antibiotic resistance profile of a bacterial infection within hours. Our machine learning algorithm Keynome™ uses MicrohmDB™, a proprietary microbial resistance database, to determine antibiotic resistance from genomic data. In a severe infection, faster treatment with the right antibiotic saves lives and reduces costs.

We are based at the Harvard Life Lab and Harvard iLab and we have a strong collaboration with the lab of Dr. Doug Kwon at the Ragon Institute of MGH, MIT and Harvard.


Jong Lee, MBA

President & CEO, Co-founder

Medical technology entrepreneur. Formerly management consultant at Monitor Group, focused on medtech commercialization, and Senior VP of Marketing & Strategy at ConforMIS. BA from Harvard and MBA from Harvard Business School.

Miriam Huntley, PhD

CTO, Co-founder

Computational biologist with expertise in genomics and machine learning. After MIT Physics undergrad, earned Harvard Applied Math PhD developing theory and computational methods for analyzing biological systems and large genomic datasets.

Doug Kwon, MD, PhD

Scientific Co-founder

Infectious Disease physician at Mass. General Hospital (MGH), Assistant Professor at Harvard Medical School and a Director of Clinical Research at the Ragon Institute of MGH, MIT and Harvard. Expertise in the microbiome and its effect on immune response.

Melis Anahtar, MD, PhD

Scientific Co-founder

Clinical Pathology resident at MGH with expertise in immunology, the human microbiome, and diagnostics. After biomedical engineering degree at MIT, studied immunology on a Rhodes Scholarship in Oxford, and worked in Doug Kwon’s lab through the Harvard MD-PhD Program.

Dougal Maclaurin, PhD

Scientific Co-founder

Senior Research Scientist at Google Brain, software engineer with a background in physics and machine learning. In his PhD at Harvard, Dougal worked on Bayesian methods and deep learning, and developed Autograd, a popular machine learning library.

Nicole Billings, PhD

Director, Product Development

Molecular microbiologist with expertise in bacterial physiology and genetics. Nicole's post-doc at MIT focused on bacterial biofilms, and she later contributed as a technical lead to the development of a rapid pathogen identification assay at Draper Labs.

Yael Katan-Khaykovich, PhD

Senior Research Scientist

Molecular biologist with expertise in molecular diagnostics and epigenetics. Yael's post-doc at Harvard focused on determining mechanisms of gene regulation and chromatin dynamics, and she later worked in industry to develop a number of clinical genomic tests.

Chiahao (Kevin) Tsui, PhD

Research Scientist

Biochemist with expertise in transcriptional regulation and method development. During his PhD in the Tijan lab at UC Berkeley, Kevin developed methods to study protein-DNA interactions and identified novel histone gene regulators in Drosophila.

Ian Herriott

Manager, Sequencing Technologies

Sequencing aficionado with expertise in microbial ecology. After completing his bachelor's in Molecular Environmental Biology at UC Berkeley, Ian studied a variety of microbial communities and then managed the sequencing core at University of Alaska, Fairbanks.

Alexa Cecil

Lab Technician

During her undergrad studies in Human Biology and Masters in Public Health at UVA, Alexa optimized a microfluidic platform for micro-RNA detection in a clinical setting and performed a pilot study for an at-home HPV test.

Febriana Pangestu

Lab Technician

As an undergraduate at Iowa State University, Febriana worked in a plant metabolism lab and completed her studies in biochemistry.

Michael Kumcu

Lab Technician

After studying Neuroscience at Bucknell University, Michael earned his Masters in Neurochemistry from Stockholm University where he studied the effects of post-translational modifications on cellular localization and protein interactions.



Apr 27 2018

The 10 Hottest Medtech Startups of 2018
DZD voted as a top 10 medical device startup

Apr 13 2018

20 Medical Device Startups You Need to Know
DZD highlighted as top medical device startup

Feb 19 2018
Jan 23 2018
Dec 15 2017

PULSE@MassChallenge Announces 2018 Cohort of Top Digital Health Startups
DZD selected from over 500 applicants to participate in accelerator

Oct 18 2017

The Refinery announces winners of Fueling the Growth Pitch Competition
DZD wins $15,000 first place award during Women Entrepreneurs Boston event

Oct 15 2017

Life Lab Nurtures Early Stage Startup
DZD featured in Harvard Business School Alumni Bulletin

Sep 29 2017

A Startup Takes on Antibiotic Resistance
DZD Mission Explained by Clifton Leaf, Editor-in-Chief, Fortune

Sep 26 2017

Day Zero Diagnostics is 2017 MedTech Innovator Global Competition Winner
DZD wins $350,000 in non-dilutive funding at the MedTech Innovator Conference

Sept 21 2017
Sep 19 2017

Finalists Announced for Annual MedTech Industry $500K Competition
DZD Selected as one of 4 finalists to compete for cash awards

Aug 7 2017

DZD Announces Completion of $3M Series Seed Raise
Funding to support completion of technical proof of concept and prototype development

Jul 31 2017

The New World Order Of Artificial Intelligence
DZD highlighted in Forbes article on AI trends

May 31 2017

MedTech Innovator Announces Startups Selected for Global Accelerator
DZD one of 20 participants in the industry's premier accelerator

May 23 2017

MassChallenge Boston Announces 2017 Accelerator Cohort
DZD selected from over 1,500 applicants to participate in program

Mar 10 2017

Finalists Named in Harvard President's Innovation Challenge
DZD named one of 5 healthcare finalists in innovation challenge

Feb 12 2017

Harvard Innovation Labs Story: Miriam Huntley
Miriam interviewed on the Harvard Innovation Labs podcast

Nov 9 2016

Life Lab Builds on Cross-disciplinary Approach
Day Zero Diagnostics featured in opening ceremony of the Pagliuca Harvard Life Lab

Aug 23 2016

Kwon Awarded MGH DOM Innovation Grant
The Kwon Lab wins innovation grant to pursue bacterial resistance diagnostics

Aug 2 2016

Here Are 8 Digital Health Startups to Watch in Boston
BostInno features Day Zero Diagnostics as a startup to watch

Mar 23 2016

Day Zero Diagnostics Named 2016 HBSAB New Venture Competition Winner
DZD wins Harvard Business School Association of Boston Alumni New Venture Contest


Winner, New England Region (2016)

Winner, Pilot Innovation Grant (2016)

Venture in Residence, Harvard iLab & Life Lab (2016-2017)

Audience Choice, MIT Sloan Healthcare Innovation Prize (2017)

Winner, Boston Pitch Competition (2017), Global Competition Winner (2017)

Finalist, Harvard President's Innovation Challenge (2017)

Finalist, MassChallenge Accelerator Program (2017)

Winner, Fueling the Growth Boston Pitch Competition (2017)

Finalist, PULSE@MassChallenge Digital Health Accelerator Program (2017)

Pagliuca Harvard Life Lab, 127 Western Ave, Boston, MA 02134

Copyright © 2018 Day Zero Diagnostics Inc.